Here are some examples of keywords you can target based off of a url.
* http://ecards.com
* http://www.ecards.com
* ecards.com
* ecards com
* ecardscom
* www.ecards.com
* wwwecards.com
* www.ecards com
Yes you want to add the dots. But remember to remove the dots as well. Google is a search engine so your volumn for these keywords will be lower but you will get impressions. It's amazing how many people try to plug in a URL in to a keyword search box.
There really isn't a way to incorporate the searched for URL into your own landing page with out it looking weird. Products or words searched for are much better for this.
As far as miss spelled WORDS. Google is pretty savy and knows what people ment to type. So if your target keyword is "eCards" and you bid on "eCrdas" Google will know what the person ment to type. You will be just find bidding on the keyword "eCrdas" with the landing page showing the keyword "eCards".
I hope that all made sense :)
Best of luck!